This page/content is for Great Britain healthcare professionals only.
Pluvicto®▼ (lutetium [177Lu] vipivotide tetraxetan) is indicated for the treatment of adult patients with prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer (mCRPC) who have been treated with androgen receptor (AR) pathway inhibition and taxane-based chemotherapy or who are not medically suitable for taxanes.1
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Pluvicto mechanism of action
Pluvicto targets PSMA-positive cells, including prostate cancer cells.1
Safety profile
The efficacy and safety profile of Pluvicto + BSoC were assessed in the VISION trial.2
Dosing and administration
Pluvicto is a ready-to-use solution administered intravenously.1
AR, androgen receptor; BSoC, best standard of care; mCRPC, metastatic castration-resistant prostate cancer; PSMA, prostate-specific membrane antigen.
References:
- Pluvicto® Great Britain Summary of Product Characteristics.
- Sartor O, et al. N Engl J Med 2021;385(12):1091–1103.